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OxyContin - Time Bomb

It was touted as a miracle pill: a narcotic pain reliever that could change the lives of people suffering from chronic pain, but with little -- so its maker claimed, and thousands of doctors believed -- risk of addiction.

Since OxyContin was introduced in 1996, Canada has recorded the second-highest number of prescription opioid painkiller addictions -- and the world's second-highest death rate from overdoses.

"It's helping your pain, but then you get immune to it, so then you go to the family doctor and he says 'Well, you're gonna need more,'" a woman who became addicted to OxyContin tells the fifth estate's Linden MacIntyre. "So he puts you on the 40 milligram (dose) and you're on that for a month, and then you get used to that dose and he puts you on the 80s."

But how did a little pill that only appeared in 1996 become so big, so fast? In 1998, Canadian sales were just a few million dollars. Twelve years later they had soared to $243 million. In the U.S., sales were $3.5 billion in 2010. Though there were differences in corporate style and legal structure between Purdue in the U.S and in Canada, a similar marketing approach proved wildly successful. the fifth estate examines why medical schools, GPs and specialists in pain clinics readily embraced the drug at first, and why some have now changed their minds.

OxyContin was dropped from provincial health plans in Ontario, Saskatchewan and Atlantic Canada. The manufacturer has now stopped making it altogether, replacing it with a new formulation known as OxyNeo. But is it too little, too late? Did the drug's maker low-ball the risks? Did they know their time-release miracle pill was really a time bomb of addiction, waiting to go off?

http://rinf.com/alt-news/latest-news/what-big-pharma-does-not-want-you-to-know-about-the-opioid-epidemic/

What Big Pharma Does Not Want You to Know About the Opioid Epidemic

The prescription opioid epidemic is not new. It began when Pharma rolled out and aggressively marketed time-released opioids like Oxycontin, driving “pill mills” that distributed as many as 9 million Oxys in a six-month span. What is new is the media finally calling Pharma out on the many cagey ways it got people hooked on opioids and heroin (and continues to do so), how the FDA unabashedly helps Pharma with shocking new approvals, and how people in real pain, especially the poor and African Americans, are some of the hidden victims of the epidemic. When all the reports are in, the Pharma-driven opioid epidemic may be one of the biggest and deadliest cons in recent history.

Your Patients Won’t Get Addicted, We Promise!

When Purdue Pharma and other Pharma companies began to aggressively market opioids for even minor pain, promising practitioners they were not addictive, it had been decades since the need to tightly control narcotics had been the mandate. Many newly graduating doctors, young medical professionals and their patients did not remember the opiate addictions of the 1930s, ’40s and ’50s and the many U.S. troops who got hooked on heroin in Vietnam. (Certainly no one remembered the notorious opium dens of early America.) Why should these drugs be so highly restricted, said Pharma, banking on the U.S.’ short memory. Why should they be restricted to short-term surgical pain, accidents and treatment of cancer and terminal pain conditions?

The misinformation was abetted by a perverse pro-opioid movement of users who claim the real problem is the media’s “misunderstanding” of opioids and overly tight controls on the pills. (After all, you are never addicted until your source is cut off.)  Such vocal defenders are not a coincidence. They are the result of Pharma’s deliberate, multimillion-dollar campaigns to cast chronic pain and other nonmalignant pain conditions as requiring opioids and Pharma’s thriving parallel addiction business. Twenty years ago, none of the pain conditions now presented as requiring opioids would have been presented that way. Nor were between 40 and 52 people a day dying from opioids.

Read more: What Big Pharma Does Not Want You to Know About the Opioid Epidemic